Dr.pharmacist
Flonase

Flonase

fluticasone propionate

OTC DrugFlonase
Reviewed by Younghun Cho

Pharmacist's Verdict

Flonase is a highly effective nasal spray for treating a wide range of allergy symptoms, making it a top choice for people with moderate to severe seasonal or year-round allergies. It's especially good for those who don't get enough relief from antihistamines alone.

Ingredient Analysis

Fluticasone Furoate

Pros & Cons

Pros

  • Highly effective for a wide range of allergy symptoms including runny nose, stuffiness, sneezing, itchy nose, and even itchy, watery eyes.
  • Works directly in the nose to reduce inflammation caused by allergens.
  • Starts working within 12 hours, with its full effect seen after a few days of regular use.
  • Can be used daily for ongoing, consistent allergy relief.
  • Available over-the-counter without needing a prescription.

Cons

  • May cause local side effects like nosebleeds, irritation, or an unpleasant taste/smell in the nose.
  • Not for immediate relief; it takes several days of consistent use for the full benefit to be felt.
  • Long-term use could potentially lead to rare eye problems like glaucoma or cataracts, especially for those already at risk; consult a doctor if you have these conditions.
  • Not safe for use in children under 2 years of age.
  • Requires consistent daily use to maintain effectiveness.

Safety Information

Warnings

Warnings Only for use in the nose. Do not spray into your eyes or mouth. Do not use • in children under 2 years of age • to treat asthma • if you have an injury or surgery to your nose that is not fully healed • if you have ever had an allergic reaction to this product or any of the ingredients Ask a doctor before use if you have or had glaucoma or cataracts Ask a doctor or pharmacist before use if you are taking • medicine for HIV infection (such as ritonavir) • a steroid medicine for asthma, allergies or skin rash • ketoconazole pills (medicine for fungal infection) When using this product • the growth rate of some children may be slower • stinging or sneezing may occur for a few seconds right after use • do not share this bottle with anyone else as this may spread germs • remember to te…

Is Flonase safe for you?

See pregnancy, interactions, and common concerns answered in our pharmacist safety FAQ.

Read safety review →

References

  1. 1.
    FDA Drug Label — Fluticasone Propionate

    FDA DailyMed: Fluticasone Propionate · FDA

  2. 2.
    FDA Drug Label — FLONASE SENSIMIST ALLERGY RELIEF

    FDA DailyMed: FLONASE SENSIMIST ALLERGY RELIEF · FDA

  3. 3.
    Allergic Rhinitis: A Review.

    Bernstein JA, Bernstein JS, Makol R, et al., JAMA, 2024 · PubMed

  4. 4.
    Eosinophilic Esophagitis: A Review.

    Muir A, Falk GW, JAMA, 2021 · PubMed

  5. 5.
    Intranasal antihistamines and corticosteroids in allergic rhinitis: A systematic review and meta-analysis.

    Sousa-Pinto B, Vieira RJ, Brozek J, et al., The Journal of allergy and clinical immunology, 2024 · PubMed

  6. 6.
    Salmeterol/fluticasone propionate combination.

    Spencer CM, Jarvis B, Drugs, 1999 · PubMed