Dr.pharmacist
Life Extension Two-Per-Day Multivitamin

Life Extension Two-Per-Day Multivitamin

SupplementLife Extension Two-Per-Day Multivitamin
Reviewed by Younghun Cho

Pharmacist's Verdict

Life Extension Two-Per-Day is a high-potency, premium multivitamin best suited for individuals seeking higher-than-average nutrient doses and easily absorbed vitamin forms. It's an excellent, comprehensive formula, though it may be more than what the average person needs.

Ingredient Analysis

Methylcobalamin (Vitamin B12) & L-5-methyltetrahydrofolate (Folate)

Pyridoxal 5'-phosphate (Vitamin B6)

Quercetin

Alpha-lipoic acid

Selenium (as SelenoExcell® High Selenium Yeast)

Pros & Cons

Pros

  • Uses highly bioavailable forms of vitamins, such as methylated B vitamins, which are easier for the body to use.
  • Provides doses that are often significantly higher than the recommended daily minimums.
  • Includes added antioxidants like quercetin and alpha-lipoic acid not found in most basic multivitamins.
  • The two-per-day dosage helps maintain more stable nutrient levels in your body compared to a single large pill.
  • The company provides a Certificate of Analysis for its products, ensuring quality and purity.

Cons

  • Significantly more expensive than typical drugstore multivitamins.
  • High doses of some nutrients can cause minor side effects like bright yellow urine (from B vitamins) or nausea if taken on an empty stomach.
  • The high potency is unnecessary for people who already eat a well-balanced, nutrient-rich diet.
  • Contains soy, which is a common allergen.
  • Requires remembering to take two separate doses, which can be inconvenient.

References

  1. 1.
    Improving nutrition in cystic fibrosis: A systematic literature review.

    Mielus M, Sands D, Woynarowski M, Nutrition (Burbank, Los Angeles County, Calif.), 2022 · PubMed

  2. 2.
    Hereditary Fructose Intolerance.

    Adam MP, Bick S, Mirzaa GM, et al., , 1993 · PubMed

  3. 3.
    Antioxidant vitamins and mineral supplementation, life span expansion and cancer incidence: a critical commentary.

    Dolara P, Bigagli E, Collins A, European journal of nutrition, 2012 · PubMed

  4. 4.
    Vitamins in the prevention or delay of cognitive disability of aging.

    Dror Y, Stern F, Gomori MJ, Current aging science, 2014 · PubMed

  5. 5.
    Complementary and Integrative Medicine Prevalence and Utilization in International Military and Veteran Settings and Communities: A Systematic Review.

    Bayes J, Palencia J, Wardle J, Military medicine, 2024 · PubMed