Dr.pharmacist
Mucinex DM

Mucinex DM

guaifenesin/dextromethorphan

OTC DrugMucinex DM
Reviewed by Younghun Cho

Pharmacist's Verdict

Mucinex DM is a good choice for adults and children 12 years and older who are dealing with both a chesty cough and a dry, irritating cough from a cold or flu. It helps clear mucus and calm your cough at the same time.

Ingredient Analysis

Guaifenesin

Dextromethorphan HBr

Pros & Cons

Pros

  • Targets two main cold symptoms (wet cough and dry cough) with one medication.
  • Extended-release formula means you take it less often, usually every 12 hours.
  • Contains well-known and effective ingredients for cough and chest congestion.
  • Helps thin and loosen mucus, making coughs more productive and easier to clear.

Cons

  • Not suitable for children under 12 years old.
  • Can interact dangerously with certain antidepressant medications called MAOIs, even up to 2 weeks after stopping them.
  • May cause side effects like dizziness, drowsiness, nausea, or upset stomach in some people.
  • If you only have one symptom (either just chest congestion or just a dry cough), using a product with two ingredients might be unnecessary.

Safety Information

Warnings

Warnings Do not use for children under 12 years of age if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough accompanied by too much phlegm (mucus) When using this product do not use more than directed Stop use and ask a doctor if cough lasts more than 7 days, comes back, or occurs with fever, rash, or persistent headache. These could be signs of a serious illness. If pregnant or bre…

Is Mucinex DM safe for you?

See pregnancy, interactions, and common concerns answered in our pharmacist safety FAQ.

Read safety review →

References

  1. 1.
    FDA Drug Label — Mucus Relief DM

    FDA DailyMed: Mucus Relief DM · FDA

  2. 2.
    FDA Drug Label — Mucinex DM Maximum Strength

    FDA DailyMed: Mucinex DM Maximum Strength · FDA

  3. 3.
    Adolescent abuse of dextromethorphan.

    Schwartz RH, Clinical pediatrics, 2005 · PubMed

  4. 4.
    Over-the-counter (OTC) medications for acute cough in children and adults in community settings.

    Smith SM, Schroeder K, Fahey T, The Cochrane database of systematic reviews, 2014 · PubMed

  5. 5.
    Drugs for cough.

    The Medical letter on drugs and therapeutics, 2018 · PubMed

  6. 6.