Dr.pharmacist
Robitussin

Robitussin

dextromethorphan/guaifenesin

OTC DrugRobitussin
Reviewed by Younghun Cho

Pharmacist's Verdict

This combination product is a good choice for adults and older children dealing with both a productive (mucus-filled) cough and an irritating dry cough, offering effective relief from common cold symptoms.

Ingredient Analysis

Dextromethorphan HBr

Guaifenesin

Pros & Cons

Pros

  • Effectively calms coughs due to colds or flu (dextromethorphan).
  • Helps loosen and thin mucus, making it easier to cough up and clear from the chest (guaifenesin).
  • Provides relief for two common cough types (wet and dry).
  • Widely available over-the-counter, making it easy to access.
  • The combination of ingredients can be more convenient than taking two separate medications.

Cons

  • Has a serious drug interaction with MAOI medications (certain drugs for depression, psychiatric conditions, or Parkinson's disease); it must not be used if you are taking these or for 2 weeks after stopping them.
  • Can cause side effects like drowsiness, dizziness, or stomach upset in some people.
  • May not be suitable for chronic coughs, coughs with asthma, or coughs related to more serious lung conditions without a doctor's advice.
  • Some people may not find guaifenesin as effective as they hope for thinning very thick mucus.

Safety Information

Warnings

Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have • cough that occurs with too much phlegm (mucus) • cough that lasts or is chronic such as occurs with smoking, asthma, chronic bronchitis, or emphysema Stop use and ask a doctor if cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of…

Is Robitussin safe for you?

See pregnancy, interactions, and common concerns answered in our pharmacist safety FAQ.

Read safety review →

References

  1. 1.
    FDA Drug Label — Akin Cough Formula DM

    FDA DailyMed: Akin Cough Formula DM · FDA

  2. 2.
    FDA Drug Label — Robitussin Sugar-Free Dye-Free Cough Plus Chest Congestion DM

    FDA DailyMed: Robitussin Sugar-Free Dye-Free Cough Plus Chest Congestion DM · FDA

  3. 3.
    Adolescent abuse of dextromethorphan.

    Schwartz RH, Clinical pediatrics, 2005 · PubMed

  4. 4.
    Over-the-counter (OTC) medications for acute cough in children and adults in community settings.

    Smith SM, Schroeder K, Fahey T, The Cochrane database of systematic reviews, 2014 · PubMed

  5. 5.
    Drugs for cough.

    The Medical letter on drugs and therapeutics, 2018 · PubMed

  6. 6.