Reviewed by Younghun Cho
Pharmacist's Verdict
The Ordinary Retinol 0.5% in Squalane is an excellent and highly affordable serum for people ready to step up from a beginner retinol to tackle fine lines and uneven texture, but expect some initial irritation.
Ingredient Analysis
Retinol (0.5%)
Squalane
Simmondsia Chinensis (Jojoba) Seed Oil
Pros & Cons
Pros
- Effective mid-strength concentration (0.5%) for visible anti-aging results.
- Extremely budget-friendly, making a powerful ingredient accessible to everyone.
- Simple formula with squalane helps moisturize and reduce potential dryness.
- Improves the appearance of fine lines, wrinkles, and skin texture with consistent use.
Cons
- High potential for irritation, including redness, peeling, and dryness, especially for first-time users.
- Should not be used during pregnancy or while breastfeeding.
- Must be used with daily sunscreen as it increases sun sensitivity.
- The squalane base may feel too oily for those with very oily skin types.
References
- 1.FDA Drug Label — Dove
FDA DailyMed: Dove · FDA
- 2.Human Skin Aging and the Anti-Aging Properties of Retinol.
Quan T, Biomolecules, 2023 · PubMed
- 3.Antioxidant vitamins supplementation reduce endometriosis related pelvic pain in humans: a systematic review and meta-analysis.
Zheng SH, Chen XX, Chen Y, et al., Reproductive biology and endocrinology : RB&E, 2023 · PubMed
- 4.A systematic review and meta-analysis of the effects of pasteurization on milk vitamins, and evidence for raw milk consumption and other health-related outcomes.
Macdonald LE, Brett J, Kelton D, et al., Journal of food protection, 2011 · PubMed
- 5.The importance of vitamin A in nutrition.
Dawson MI, Current pharmaceutical design, 2000 · PubMed
- 6.Vitamin A Update: Forms, Sources, Kinetics, Detection, Function, Deficiency, Therapeutic Use and Toxicity.
Carazo A, Macáková K, Matoušová K, et al., Nutrients, 2021 · PubMed