Dr.pharmacist
Nature Made Vitamin D3

Nature Made Vitamin D3

cholecalciferol

SupplementNature Made Vitamin D3
Reviewed by Younghun Cho

Pharmacist's Verdict

Nature Made Vitamin D3 is a reliable and affordable supplement for supporting bone and immune health, especially for individuals with a diagnosed deficiency or limited sun exposure.

Ingredient Analysis

Vitamin D3 (as Cholecalciferol)

Soybean Oil

Pros & Cons

Pros

  • USP Verified, which means its ingredients, potency, and manufacturing process have been tested for quality.
  • Effectively supports bone health by helping your body absorb calcium.
  • Helps maintain a healthy immune system.
  • Widely available in various strengths and is very affordable.

Cons

  • Taking excessively high doses can lead to vitamin D toxicity, as it is a fat-soluble vitamin that builds up in the body.
  • Not everyone needs to supplement; it's best to confirm a deficiency with a blood test from your doctor.
  • May interact with certain medications like steroids, some weight-loss drugs, and diuretics.
  • Can cause mild side effects like nausea or constipation in some people, particularly at high doses.

References

  1. 1.
    FDA Drug Label — Bone Liquescence

    FDA DailyMed: Bone Liquescence · FDA

  2. 2.
    Association between vitamin D supplementation and mortality: systematic review and meta-analysis.

    Zhang Y, Fang F, Tang J, et al., BMJ (Clinical research ed.), 2019 · PubMed

  3. 3.
    Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes : A Systematic Review and Meta-analysis of Individual Participant Data From 3 Randomized Clinical Trials.

    Pittas AG, Kawahara T, Jorde R, et al., Annals of internal medicine, 2023 · PubMed

  4. 4.
    Sources of vitamin D for humans.

    Benedik E, International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2022 · PubMed

  5. 5.
    Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis.

    Reid IR, Bolland MJ, Grey A, Lancet (London, England), 2014 · PubMed

  6. 6.
    Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis.

    Tripkovic L, Lambert H, Hart K, et al., The American journal of clinical nutrition, 2012 · PubMed