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Nature Made Cranberry with Vitamin C Softgels
Pharmacist Safety Review

Is Nature Made Cranberry with Vitamin C Softgels Safe?

Generic: Cranberry Extract, Vitamin C

Reviewed by Dr. Younghun ChoLast reviewed April 25, 2026

Generally yes, Nature Made Cranberry with Vitamin C Softgels are considered safe for most healthy adults when used as directed to help prevent recurrent urinary tract infections (UTIs). It is important to remember that this supplement is for prevention and should not be used to treat an active UTI.

Who Should Avoid or Consult First

  • Individuals with a history of kidney stones
  • People taking blood-thinning medications like warfarin
  • Pregnant or breastfeeding women
  • People with diabetes

Common Side Effects

  • Mild stomach upset or diarrhea — especially with higher doses
  • Nausea

Interactions to Watch For

Blood thinners (e.g., Warfarin)

Cranberry may increase the risk of bleeding when taken with these medications.

Antacids containing aluminum

Vitamin C can increase how much aluminum your body absorbs, potentially leading to higher aluminum levels.

Certain chemotherapy drugs

High doses of Vitamin C might interfere with the effectiveness of some cancer treatments.

People Also Ask

Can I take Nature Made Cranberry daily?

Yes, it is generally safe to take Nature Made Cranberry with Vitamin C daily for long-term UTI prevention. Always follow the dosage instructions on the label and discuss long-term use with your doctor if you have concerns.

Is cranberry safe during pregnancy?

If you are pregnant or breastfeeding, it's best to consult your doctor before taking any supplements, including Nature Made Cranberry with Vitamin C. While cranberry is often considered safe in food amounts, supplement doses should be discussed with a healthcare provider.

What happens if I take too much cranberry?

Taking very high doses of cranberry and Vitamin C can lead to side effects like stomach upset, diarrhea, and nausea. Extremely high doses of Vitamin C over time could also increase the risk of kidney stones in susceptible individuals. Always stick to the recommended dosage.

Can children take cranberry supplements?

Cranberry supplements are generally not recommended for children unless specifically advised and dosed by a pediatrician. Children should always have their supplement use guided by a healthcare professional.

Bottom Line

Nature Made Cranberry with Vitamin C Softgels are a good option for preventing recurrent UTIs in most healthy adults. However, they are not a substitute for medical treatment if you have an active infection, so always see a doctor for UTI symptoms.

References

  1. 1.
    FDA Drug Label — DISCOUNT DRUG MART

    FDA DailyMed: DISCOUNT DRUG MART · FDA

  2. 2.
    A systematic review of non-antibiotic measures for the prevention of urinary tract infections in pregnancy.

    Ghouri F, Hollywood A, Ryan K, BMC pregnancy and childbirth, 2018 · PubMed

  3. 3.
  4. 4.
  5. 5.
    Examination of Complementary Medicine for Treating Urinary Tract Infections Among Pregnant Women and Children.

    Hudson RE, Job KM, Sayre CL, et al., Frontiers in pharmacology, 2022 · PubMed

  6. 6.
    Non-Antibiotic Prophylaxis for Urinary Tract Infections.

    Beerepoot M, Geerlings S, Pathogens (Basel, Switzerland), 2016 · PubMed

Educational content based on FDA labeling, published research, and pharmacist review. Not a substitute for individualized medical advice.