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NOW Foods Ashwagandha
Pharmacist Safety Review

Is NOW Foods Ashwagandha Safe?

Generic: withania somnifera extract

Reviewed by Younghun ChoLast reviewed April 20, 2026

Generally yes, NOW Foods Ashwagandha is considered safe for most healthy adults when used as directed to help manage mild-to-moderate stress. It is an herbal supplement and not intended to treat or cure medical conditions like anxiety disorders or depression. Always consult a healthcare professional if you have underlying health conditions or are taking other medications.

Who Should Avoid or Consult First

  • Pregnant or breastfeeding women
  • People with autoimmune diseases such as lupus, rheumatoid arthritis, or multiple sclerosis
  • Individuals with hyperthyroidism or those taking thyroid hormone medications
  • Anyone scheduled for surgery within two weeks
  • People with stomach ulcers
  • Individuals taking medications for diabetes or high blood pressure

Common Side Effects

  • Stomach upset, nausea, or diarrhea — generally mild and uncommon
  • Drowsiness — reported in a small percentage of users, especially at higher doses
  • Rare cases of liver injury have been reported, but a direct link to ashwagandha is not always clear.

Interactions to Watch For

Immunosuppressants

Ashwagandha can stimulate the immune system, potentially reducing the effectiveness of these medications.

Sedatives or CNS depressants (including alcohol)

Ashwagandha can enhance the sedative effects, leading to increased drowsiness and impaired coordination.

Thyroid hormone medications (e.g., levothyroxine)

Ashwagandha may increase thyroid hormone levels, potentially causing symptoms of hyperthyroidism.

Diabetes medications

Ashwagandha can lower blood sugar, which might lead to dangerously low blood sugar when combined with diabetes drugs.

Blood pressure medications

Ashwagandha can lower blood pressure, potentially causing blood pressure to drop too low when taken with antihypertensive drugs.

People Also Ask

Can I take ashwagandha every day?

Yes, ashwagandha is generally safe for daily use for up to three months. The safety of continuous use beyond this period is less well-studied, so it's advisable to consult a doctor for long-term plans.

Is ashwagandha safe during pregnancy?

No, ashwagandha is not recommended for use during pregnancy or breastfeeding due to insufficient safety data. There is some concern it might increase the risk of miscarriage, though evidence is limited.

Can children take ashwagandha?

Ashwagandha is not recommended for children as there isn't enough reliable information to confirm its safety or appropriate dosage in pediatric populations. Always consult a pediatrician before giving any supplements to children.

What happens if I take too much ashwagandha?

Taking very high doses of ashwagandha can lead to significant stomach upset, vomiting, and diarrhea. In rare cases, extremely high doses might cause more severe issues, so always stick to the recommended dosage.

Bottom Line

NOW Foods Ashwagandha can be a helpful supplement for stress relief for many adults, but it's crucial to be aware of potential interactions and conditions that might make it unsafe for you. Always discuss new supplements with your doctor or pharmacist, especially if you have existing health conditions or take other medications.

References

  1. 1.
    FDA Drug Label — Adrenal and DHEA

    FDA DailyMed: Adrenal and DHEA · FDA

  2. 2.
    Effects of Ashwagandha (Withania Somnifera) on stress and anxiety: A systematic review and meta-analysis.

    Arumugam V, Vijayakumar V, Balakrishnan A, et al., Explore (New York, N.Y.), 2024 · PubMed

  3. 3.
    Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.

    Cheah KL, Norhayati MN, Husniati Yaacob L, et al., PloS one, 2021 · PubMed

  4. 4.
  5. 5.
  6. 6.
    Pharmacological evaluation of Ashwagandha highlighting its healthcare claims, safety, and toxicity aspects.

    Mandlik Ingawale DS, Namdeo AG, Journal of dietary supplements, 2021 · PubMed

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Educational content based on FDA labeling, published research, and pharmacist review. Not a substitute for individualized medical advice.